Shiga-toxigenic Escherichia coli-inoculated neonatal piglets develop kidney lesions that are comparable to those in humans with hemolytic-uremic syndrome.
نویسندگان
چکیده
Kidney lesions similar to those in humans with hemolytic-uremic syndrome were observed histologically in 82 of 122 piglets inoculated intragastrically with Shiga-toxigenic Escherichia coli but not in 29 controls. The locations of lesions matched locations where Stx-2 binding and Gb3 (globotriasylceramide receptors for Stx) were identified immunohistochemically.
منابع مشابه
Pathogenicity of Escherichia coli O157:H7 in the intestines of neonatal calves.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 73 1 شماره
صفحات -
تاریخ انتشار 2005